Psychology Reader

Prevention of Depressive Relapse by Mindfulness-Based Cognitive Therapy

John D. Teasdale, Zindel V. Segal, J. Mark G. Williams, and 3 others · 2000 · Journal of Consulting and Clinical Psychology

Role
Landmark empirical study
Difficulty
Moderate
Full work length
9 pages
Type
Journal article

Access

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Reading focus

Syllabus: How Can Working With Emotion, Awareness and Acceptance Promote Change?

Compare the proposed cognitive process with the relapse-prevention outcome and treatment-as-usual control.

Why you’re reading it. Move from short-term component evidence to sustained clinical benefit.

A question to consider. What active comparison could test whether the added program prevents recurrence through its mindfulness component rather than attention or group support?

Why this reading

Preventing another depressive episode poses a different explanatory question from improving current symptoms. Teasdale and colleagues test mindfulness-based cognitive therapy after remission, motivated by an account of how low mood can reactivate patterns of thinking. The study lets readers compare a theory of vulnerability with what a prevention trial can actually establish.

Before you read

Mindfulness-based cognitive therapy combines attention practices with cognitive-therapy ideas about relating to thoughts and feelings. Treatment as usual allows ordinary care; it does not match the added program for time, group contact, or expectations. A survival analysis examines time to an event while accounting for participants observed for different lengths of time.

Read for

  1. Distinguish the proposed process of cognitive reactivation from the randomized comparison and measured relapse/recurrence outcome. Is the mechanism directly isolated?
  2. Follow the eligibility rules: participants were in remission, had recurrent depression, and were not taking antidepressants at baseline. Which populations do these rules leave out?
  3. Examine the interaction with previous episode count and the much smaller two-episode group. How much confidence should an initial subgroup pattern carry?

Consider afterwards

  1. What comparison could distinguish the specific contribution of mindfulness from group support and additional clinical attention?
  2. How would the evidence required for an acute-treatment claim differ from the evidence supplied by this prevention design?

Editorial context

The 145-person trial involved three UK and Canadian sites and followed participants through the eight-week program and a further 52 weeks. Its favorable pattern was concentrated among those with at least three previous episodes, with a small two-episode stratum. It does not establish a universal episode-count rule. Kuyken and colleagues’ later individual-participant meta-analysis broadens the prevention evidence across nine trials, while leaving uncertainty about mechanisms and moderators. Its harmonized episode categories do not directly retest the original two-versus-three threshold.